Description

2-Chloro-4-Aminophenol is a versatile halogenated aminophenol derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both an amine and a phenolic hydroxyl group, which makes it an essential intermediate for creating complex molecular architectures. It is primarily sought after by manufacturers in the pharmaceutical, agrochemical, and specialty dye industries for the development of active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with analgesic or antipyretic properties.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators, leveraging its halogen and amine functionalities.
• Dye and Pigment Manufacturing: Serves as a coupling agent and intermediate for producing azo dyes and other complex colorants.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polymers and resins, including epoxy hardeners.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compounds.
• Photographic Chemicals: Can be utilized in the formulation of certain photographic developers and related fine chemicals.

Basic Information

Product Name	2-Chloro-4-Aminophenol
CAS No.	399964-52-1
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	4-Amino-2-chlorophenol; 2-Chloro-4-hydroxyaniline; 1-Amino-5-chloro-2-hydroxybenzene; 4-Amino-2-chloro-1-hydroxybenzene; 2-Chloro-1-hydroxy-4-aminobenzene; 5-Chloro-2-hydroxyaniline; 2-Chloro-4-aminophenol; 4-Amino-2-chlorophenol
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Aminophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the rigorous standards required for pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	135 - 140 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.