Description

1-Boc-3-Azetidinone is a protected azetidinone derivative, a crucial building block in advanced organic synthesis. Its primary value lies in serving as a versatile intermediate for constructing complex nitrogen-containing heterocycles, particularly β-lactam antibiotics and other pharmacologically active molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel β-lactam antibiotics and other nitrogen-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used for the construction of complex azetidine and pyrrolidine ring systems prevalent in drug discovery.
• Protease Inhibitor Research: Serves as a core scaffold in the development of protease inhibitors for therapeutic applications.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents with specific biological activity.
• Material Science Research: Utilized in the synthesis of specialized polymers and ligands for catalytic systems.

Basic Information

Product Name	1-Boc-3-Azetidinone
CAS No.	398489-26-4
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-azetidinone; 3-Azetidinone, 1-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 3-oxoazetidine-1-carboxylate; 1-Boc-azetidin-3-one; Boc-Azetidinone; 1-N-Boc-3-azetidinone; 1-(tert-Butyloxycarbonyl)azetidin-3-one
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Azetidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.