Description

n-(2-Hydroxyethyl)-4-Aza-9-Crown-3 is a specialized aza-crown ether derivative, a key building block in supramolecular chemistry and coordination chemistry. Its molecular structure, featuring a nitrogen atom within a 9-membered polyether ring and a pendant hydroxylethyl arm, provides selective binding affinity for specific cations, making it invaluable for designing advanced materials and catalysts. This compound is primarily sought by researchers and manufacturers in the pharmaceutical, chemical synthesis, and sensor technology sectors for developing novel separation media, phase-transfer catalysts, and ion-selective components.

Application

• Phase-Transfer Catalyst: Facilitates reactions between reagents in immiscible phases, particularly useful in organic synthesis and polymerization processes.
• Ionophore for Sensors: Serves as a key selective component in the development of ion-selective electrodes (ISEs) and optical chemical sensors for cation detection.
• Metal Ion Extraction & Separation: Used in solvent extraction systems for the selective recovery, purification, or removal of specific metal ions from complex mixtures.
• Pharmaceutical Intermediate: Acts as a sophisticated building block for synthesizing complex drug molecules, particularly those requiring specific metal-binding or delivery properties.
• Polymer Modification: Incorporated into polymer backbones to create materials with enhanced ion-binding capacity for filtration, catalysis, or smart material applications.
• Research & Development: Essential tool in academic and industrial R&D for studying host-guest chemistry, cation transport mechanisms, and new supramolecular assemblies.

Basic Information

Product Name	n-(2-Hydroxyethyl)-4-Aza-9-Crown-3
CAS No.	397246-46-7
Molecular Formula	C9H19NO4
Molecular Weight	205.25 g/mol
Synonyms	1-Aza-4,7,10-trioxacyclododecane-12-ethanol; 4-Aza-9-crown-3-ethanol; 2-(1-Aza-4,7,10-trioxacyclododecan-12-yl)ethanol; 12-(2-Hydroxyethyl)-1-aza-4,7,10-trioxacyclododecane; Hydroxyethyl Aza-9-Crown-3; HEAC3; N-(2-Hydroxyethyl)-1-aza-4,7,10-trioxacyclododecane
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxyethyl)-4-Aza-9-Crown-3 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.