Description

Carbamic Acid, [(1R)-1-Ethyl-1-(Hydroxymethyl)-2-Propenyl]-, 1,1-Dimethylethyl is a chiral, protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a high-purity, stereochemically defined building block, enabling the precise construction of complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Synthesis: Serves as a protected amino acid component for constructing non-natural peptide analogs with enhanced stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective synthesis.
• Chemical Biology Research: Employed as a molecular probe or building block in the study of enzyme mechanisms and protein-protein interactions.
• Custom Synthesis Projects: A valuable starting material for contract research organizations (CROs) and CDMOs working on client-specific complex molecule synthesis.
• Academic Research: Utilized in university laboratories for methodological development in stereocontrolled organic synthesis.

Basic Information

Product Name	Carbamic Acid, [(1R)-1-Ethyl-1-(Hydroxymethyl)-2-Propenyl]-, 1,1-Dimethylethyl
CAS No.	391678-40-3
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl N-[(1R)-1-ethyl-1-(hydroxymethyl)prop-2-en-1-yl]carbamate; (R)-tert-Butyl (1-ethyl-1-(hydroxymethyl)allyl)carbamate; (R)-1-((tert-Butoxycarbonyl)amino)-1-ethyl-but-3-en-1-ol; BOC-Protected Chiral Amino Alcohol Derivative; N-Boc-1-amino-1-ethyl-3-buten-1-ol (R-enantiomer); Chiral Tert-Butyl Carbamate; 391678-40-3
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1R)-1-Ethyl-1-(Hydroxymethyl)-2-Propenyl]-, 1,1-Dimethylethyl adheres to stringent internal quality standards, ensuring high chemical and enantiomeric purity for research and development applications. Each batch is characterized by advanced analytical techniques including HPLC, GC, and chiral analysis. Certificates of Analysis (COA) detailing purity, identity, and chiral excess are provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.