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2-(Acetylamino)-2-Deoxy-3-o-Benzoyl-4,6-o-Benzylidene-D-Galactopyranose Trichloroacetimidate CAS NO 390400-47-2
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CAS No.:390400-47-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(Acetylamino)-2-Deoxy-3-o-Benzoyl-4,6-o-Benzylidene-D-Galactopyranose Trichloroacetimidate is a sophisticated glycosyl donor, a key building block in the synthesis of complex oligosaccharides and glycoconjugates. Its value lies in its high reactivity and stereoselectivity, enabling the efficient construction of specific glycosidic linkages critical for biological activity. This advanced intermediate is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic tools.
Application
- Glycoscience Research: A critical reagent for the chemical and enzymatic synthesis of complex oligosaccharides and glycans.
- Pharmaceutical Intermediates: Used in the production of active pharmaceutical ingredients (APIs) for carbohydrate-based therapeutics, including antiviral and anticancer agents.
- Glycoconjugate Vaccine Development: Serves as a key building block for synthesizing antigenic carbohydrate moieties linked to carrier proteins.
- Glycobiology Probes: Enables the creation of labeled or modified sugars for studying carbohydrate-protein interactions and metabolic pathways.
- Process Development: Utilized in scaling up synthetic routes for glycosylated natural products and novel biomaterials.
Basic Information
| Product Name | 2-(Acetylamino)-2-Deoxy-3-o-Benzoyl-4,6-o-Benzylidene-D-Galactopyranose Trichloroacetimidate |
| CAS No. | 390400-47-2 |
| Molecular Formula | C24H23Cl3N2O7 |
| Molecular Weight | 557.81 g/mol |
| Synonyms | 2-Acetamido-2-deoxy-3-O-benzoyl-4,6-O-benzylidene-D-galactopyranosyl Trichloroacetimidate; 2-Acetamido-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-D-galactopyranosyl Trichloroacetimidate; GalNAc Trichloroacetimidate Derivative; Benzylidene-protected GalNAc Donor; Glycosyl Trichloroacetimidate Donor; 390400-47-2; D-Galactopyranose, 2-(acetylamino)-2-deoxy-3-O-benzoyl-4,6-O-(phenylmethylene)-, 1-(2,2,2-trichloroethanimidate) |
| EINECS | Contact for details |
Quality Control
Our high-purity glycosylation reagents are produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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