Description

4-Aminomethyltetrahydropyran Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Chiral Synthesis: Used as a versatile chiral precursor for constructing complex molecules with defined stereochemistry in asymmetric synthesis.
• Agrochemical Research: Serves as a key component in the development of new pesticides and herbicides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Acts as a starting material for the manufacture of high-value specialty chemicals and advanced polymers.

Basic Information

Product Name	4-Aminomethyltetrahydropyran Hydrochloride
CAS No.	389621-78-7
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; Tetrahydro-2H-pyran-4-methanamine hydrochloride; 4-Piperidinemethanol, tetrahydro-, hydrochloride; 4-(Aminomethyl)tetrahydropyran HCl; THP-4-methanamine hydrochloride; 4-Aminomethyltetrahydropyran HCl; (Tetrahydro-2H-pyran-4-yl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Aminomethyltetrahydropyran Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.