Description

2-(6-Chloro-1-Methyl-1H-Indol-3-Yl)Acetic Acid is a high-purity indole acetic acid derivative, serving as a critical synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its precise molecular structure, which enables the construction of complex molecules targeting specific biological pathways. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and life science sectors who require reliable, high-quality building blocks for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new therapeutic candidates.
• Agrochemical Synthesis: Intermediate for developing new generation plant growth regulators or selective herbicides.
• Biochemical Tool Compound: Serves as a precursor for labeled probes or inhibitors used in biochemical and pharmacological assays.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Custom Synthesis & Contract Manufacturing: A starting material for specialized custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	2-(6-Chloro-1-Methyl-1H-Indol-3-Yl)Acetic Acid
CAS No.	388574-11-6
Molecular Formula	C11H10ClNO2
Molecular Weight	223.66 g/mol
Synonyms	6-Chloro-1-methyl-1H-indole-3-acetic acid; (6-Chloro-1-methyl-1H-indol-3-yl)acetic acid; 2-(6-Chloro-1-methylindol-3-yl)acetic acid; 6-Chloro-1-methylindole-3-acetic acid; 1-Methyl-6-chloroindole-3-acetic acid; 388574-11-6; 2-(6-Chloro-1-methyl-1H-indol-3-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-(6-Chloro-1-Methyl-1H-Indol-3-Yl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and current industry standards for research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.