Description

4-Hydroxy-6-(Trifluoromethyl)-2H-Pyran-2-One is a high-value fluorinated heterocyclic building block. This compound matters for its unique trifluoromethyl-substituted pyranone structure, which is critical for modulating the physicochemical properties of advanced molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex fluorinated heterocycles and fine chemicals in research laboratories.
• Material Science Research: Investigated for potential use in the synthesis of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	4-Hydroxy-6-(Trifluoromethyl)-2H-Pyran-2-One
CAS No.	387866-40-2
Molecular Formula	C6H3F3O3
Molecular Weight	180.08 g/mol
Synonyms	6-(Trifluoromethyl)-4-hydroxy-2H-pyran-2-one; 4-Hydroxy-6-trifluoromethyl-2H-pyran-2-one; 4-Hydroxy-6-(trifluoromethyl)-2-pyranone; 6-Trifluoromethyl-4-hydroxypyran-2-one; 4-Hydroxy-6-(trifluoromethyl)-2-pyrone; 387866-40-2; 4-Hydroxy-6-(trifluoromethyl)pyran-2-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-6-(Trifluoromethyl)-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.