Description

[2-(Trimethylammonium)Ethyl] Toluenethiosulfonate Bromide is a specialized quaternary ammonium salt derivative with a thiosulfonate functional group, offering unique reactivity as an alkylating agent and a source of electrophilic sulfur. This compound matters for its role as a key synthetic intermediate in advanced organic and medicinal chemistry, enabling the introduction of functionalized sulfur-containing motifs. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules and developing novel chemical entities.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where a sulfur-based pharmacophore is critical.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or plant growth regulators with modified activity profiles.
• Chemical Biology Probe Development: Employed to create activity-based probes for labeling and studying proteins, leveraging its reactive thiosulfonate group.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing cationic and sulfur-containing groups into polymer backbones to alter material properties.
• Organic Synthesis Reagent: Utilized as an electrophilic sulfenylating or alkylating agent in multi-step synthetic routes to construct complex heterocycles or natural product analogs.
• Surface Functionalization: Applied to modify material surfaces (e.g., silica, gold) to create specific chemical interfaces for catalysis or sensing applications.

Basic Information

Product Name	[2-(Trimethylammonium)Ethyl] Toluenethiosulfonate Bromide
CAS No.	386229-80-7
Molecular Formula	C₁₃H₂₂BrNO₂S₂
Molecular Weight	384.35 g/mol
Synonyms	2-[(Trimethylammonio)ethyl] 4-methylbenzenethiosulfonate bromide; S-[2-(Trimethylammonio)ethyl] 4-methylbenzenesulfonothioate bromide; p-Toluenesulfonothioic acid S-[2-(trimethylammonio)ethyl] ester bromide; (2-Trimethylammonioethyl) tosylsulfonate bromide; TMAE-TosSBr; [2-(N,N,N-Trimethylammonium)ethyl] tosyl thiosulfonate bromide; 4-Methylbenzenesulfonothioic acid S-[2-(trimethylammonio)ethyl] ester bromide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of [2-(Trimethylammonium)Ethyl] Toluenethiosulfonate Bromide is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.