Description

6-Amino-3-tert-Butyl-4-(4-Isopropoxy-3-Methoxyphenyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole chemical class. This compound is critical for the research and development of novel therapeutic agents, particularly due to its complex heterocyclic structure which serves as a key scaffold in medicinal chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for synthesizing potential drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Acts as a starting material for developing specialized probes to study biological pathways and enzyme functions.
• Organic Synthesis: Employed in advanced organic synthesis for constructing complex heterocyclic frameworks with potential biological activity.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process development for clients.

Basic Information

Product Name	6-Amino-3-tert-Butyl-4-(4-Isopropoxy-3-Methoxyphenyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	385389-23-1
Molecular Formula	C₂₂H₂₈N₄O₃
Molecular Weight	396.49 g/mol
Synonyms	6-Amino-3-tert-butyl-4-(4-isopropoxy-3-methoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-(tert-butyl)-4-[4-(propan-2-yloxy)-3-methoxyphenyl]-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 385389-23-1; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-(1,1-dimethylethyl)-4-[4-(1-methylethoxy)-3-methoxyphenyl]-2,4-dihydro-; 6-Amino-3-tert-butyl-4-(4-isopropoxy-3-methoxyphenyl)-2H,4H-pyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-3-tert-Butyl-4-(4-Isopropoxy-3-Methoxyphenyl)-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.