Description

4H-1-Benzopyran-4-One, 6-Chloro-3-Hydroxy-2-(3,4,5-Trimethoxyphenyl)- is a high-purity, synthetically derived chromone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile synthetic intermediate for developing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents and specialized chemical libraries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Used to create tool compounds for studying biological processes and enzyme functions.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and chromone analogs.
• Academic Research: Employed in universities and research institutes for methodological development and exploring new chemical reactions.

Basic Information

Product Name	4H-1-Benzopyran-4-One, 6-Chloro-3-Hydroxy-2-(3,4,5-Trimethoxyphenyl)-
CAS No.	385381-94-2
Molecular Formula	C18H15ClO6
Molecular Weight	362.76 g/mol
Synonyms	6-Chloro-3-hydroxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one; 6-Chloro-3-hydroxy-2-(3,4,5-trimethoxyphenyl)chromone; 2-(3,4,5-Trimethoxyphenyl)-6-chloro-3-hydroxy-4H-chromen-4-one; Chromone derivative 385381-94-2; 6-Chloro-3-hydroxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.