Description

6-Amino-2-trifluoromethyl-chromen-4-one is a high-purity, functionalized chromenone derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique combination of a chromenone scaffold with both amino and trifluoromethyl functional groups, enabling the synthesis of novel compounds with tailored properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate these valuable motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in creating new active ingredients for crop protection products, leveraging the bioactivity of the chromenone core and the metabolic stability imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a monomer or functional additive in the development of advanced organic electronic materials, such as OLEDs and fluorescent sensors.
• Chemical Biology Probe: Utilized in medicinal chemistry to construct molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental research in heterocyclic and fluorine chemistry.

Basic Information

Product Name	6-Amino-2-trifluoromethyl-chromen-4-one
CAS No.	383371-02-6
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	6-Amino-2-(trifluoromethyl)-4H-chromen-4-one; 6-Amino-2-(trifluoromethyl)-4H-1-benzopyran-4-one; 2-Trifluoromethyl-6-amino-chromone; 6-Amino-2-trifluoromethylchromone; 4H-1-Benzopyran-4-one, 6-amino-2-(trifluoromethyl)-; 383371-02-6
EINECS	Contact for details

Quality Control

Every batch of 6-Amino-2-trifluoromethyl-chromen-4-one is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.