Description

3-Amino-4,4-Diphenyl-Butanoic Acid is a high-purity, non-natural amino acid derivative featuring a diphenyl-substituted butanoic acid backbone. This compound matters as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Peptidomimetics & Constrained Peptide Design: Used to introduce rigidity and specific spatial orientation into peptide chains, enhancing stability and biological activity.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand & Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for use in stereoselective transformations.
• Chemical Biology & Proteomics: Utilized as a molecular probe or a tagged amino acid analog to study protein structure, function, and interactions.
• Academic & Industrial Research: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Amino-4,4-Diphenyl-Butanoic Acid
CAS No.	380861-91-6
Molecular Formula	C₁₆H₁₇NO₂
Molecular Weight	255.31 g/mol
Synonyms	4,4-Diphenyl-3-aminobutanoic Acid; 3-Amino-4,4-diphenylbutyric Acid; DL-3-Amino-4,4-diphenylbutanoic Acid; (±)-3-Amino-4,4-diphenylbutanoic Acid; 4,4-Diphenyl-3-aminobutyric Acid; β-Amino-gamma,γ-diphenylbutyric Acid; 3-Amino-4,4-diphenylbutanoic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-4,4-Diphenyl-Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.