Description

2H-Pyran-4-Methanol, Tetrahydro-3-Hydroxy- (9Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in classes like antivirals, neuraminidase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where its stereochemistry can influence biological activity.
• Fine Chemical Production: Serves as a crucial building block in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Material Science Research: Investigated as a monomer or precursor for novel polymers and functional materials with specific optical or chemical properties.

Basic Information

Product Name	2H-Pyran-4-Methanol, Tetrahydro-3-Hydroxy- (9Ci)
CAS No.	380665-15-6
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	3-Hydroxytetrahydro-2H-pyran-4-methanol; Tetrahydro-3-hydroxy-2H-pyran-4-methanol; 4-(Hydroxymethyl)tetrahydro-2H-pyran-3-ol; (3R,4S)-4-(Hydroxymethyl)tetrahydro-2H-pyran-3-ol (for specific enantiomer); 3-Hydroxy-4-hydroxymethyltetrahydropyran; A potential intermediate for Oseltamivir synthesis
EINECS	Contact for details

Quality Control

Our 2H-Pyran-4-Methanol, Tetrahydro-3-Hydroxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.