Description

2H-Pyran, 2-Ethyl-6-Ethynyl-5,6-Dihydro-3-Methyl-, (2R,6R)- (9Ci) is a chiral, substituted dihydropyran derivative featuring an ethynyl functional group, making it a valuable synthetic intermediate. This compound is significant for its role in constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a functionalized pyran ring structure.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or polymers with tailored optical properties.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic synthesis, including cycloaddition and cross-coupling reactions.

Basic Information

Item	Details
Product Name	2H-Pyran, 2-Ethyl-6-Ethynyl-5,6-Dihydro-3-Methyl-, (2R,6R)- (9Ci)
CAS No.	380355-92-0
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(2R,6R)-2-Ethyl-6-ethynyl-5,6-dihydro-3-methyl-2H-pyran; (2R,6R)-2-Ethyl-6-ethynyl-3-methyl-5,6-dihydro-2H-pyran; 2-Ethyl-6-ethynyl-5,6-dihydro-3-methyl-2H-pyran, (2R,6R)-; Dihydro-2H-pyran derivative; Chiral dihydropyran; Ethynyl dihydropyran; CAS 380355-92-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, detailing results from analytical methods including HPLC, GC, and NMR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.