Description

Methyl (S)-Hexahydropyridazine-3-Carboxylate Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized heterocyclic structure, which are crucial for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts efficacy and environmental profile.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems for stereoselective transformations.
• Peptidomimetic Chemistry: The hexahydropyridazine core is a valuable scaffold for designing peptide analogs and conformationally restricted bioactive molecules.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of complex natural product analogs.
• Custom Synthesis Projects: A starting material for bespoke chemical synthesis services targeting specialized, high-value compounds.

Basic Information

Product Name	Methyl (S)-Hexahydropyridazine-3-Carboxylate Hydrochloride
CAS No.	380223-17-6
Molecular Formula	C7H15ClN2O2
Molecular Weight	194.66 g/mol
Synonyms	(S)-Methyl Hexahydropyridazine-3-carboxylate Hydrochloride; Methyl (S)-1,2-Diazinane-3-carboxylate Hydrochloride; (S)-Methyl Perhydropyridazine-3-carboxylate HCl; (3S)-Hexahydropyridazine-3-carboxylic Acid Methyl Ester Hydrochloride; L-Hexahydropyridazine-3-carboxylic Acid Methyl Ester Hydrochloride; Methyl L-Hexahydropyridazine-3-carboxylate Hydrochloride; 380223-17-6
EINECS	Contact for details

Quality Control

Our Methyl (S)-Hexahydropyridazine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.