Description

1-(4-Chloro-Benzenesulfonyl)-Piperidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide-piperidine-carboxylic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: May be employed as a ligand or precursor in the study of biological pathways and enzyme mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals.

Basic Information

Product Name	1-(4-Chloro-Benzenesulfonyl)-Piperidine-2-Carboxylic Acid
CAS No.	379223-45-7
Molecular Formula	C12H14ClNO4S
Molecular Weight	303.76 g/mol
Synonyms	1-[(4-Chlorophenyl)sulfonyl]piperidine-2-carboxylic acid; 2-Piperidinecarboxylic acid, 1-[(4-chlorophenyl)sulfonyl]-; 1-(p-Chlorobenzenesulfonyl)piperidine-2-carboxylic acid; 1-(4-Chlorophenylsulfonyl)piperidine-2-carboxylic acid; 1-(4-Chlorobenzene-1-sulfonyl)piperidine-2-carboxylic acid; 379223-45-7; 1-(4-Chloro-benzenesulfonyl)-piperidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Benzenesulfonyl)-Piperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.