Description

2-Cyclopenten-1-One,4,5-Dihydroxy-2-(1E)-1-Propenyl-,(4R,5S)-Rel-(9Ci) is a high-purity, stereochemically defined cyclopentenone derivative that serves as a critical chiral building block and synthetic intermediate. Its unique dihydroxy-substituted structure with a propenyl side chain makes it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development in advanced pharmaceutical synthesis, agrochemical discovery, and fine chemical manufacturing, where control over molecular geometry is paramount for biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandin analogs, antiviral agents, and other bioactive molecules requiring specific stereocenters.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage its reactive carbonyl and hydroxyl functionalities.
• Fine Chemical Synthesis: Serves as a versatile precursor for fragrances, flavors, and specialty chemicals where the cyclopentenone core is a desired structural motif.
• Academic & Industrial R&D: Employed in methodological chemistry research, including studies on asymmetric synthesis, cycloaddition reactions, and natural product total synthesis.
• Material Science Precursor: Potential use in synthesizing specialized polymers or organic electronic materials due to its conjugated system and functional handles for polymerization.

Basic Information

Product Name	2-Cyclopenten-1-One,4,5-Dihydroxy-2-(1E)-1-Propenyl-,(4R,5S)-Rel-(9Ci)
CAS No.	377735-36-9
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(4R,5S)-rel-4,5-Dihydroxy-2-[(1E)-1-propenyl]-2-cyclopenten-1-one; 4,5-Dihydroxy-2-[(1E)-propen-1-yl]-2-cyclopenten-1-one (rel-(4R,5S)-); 2-Cyclopenten-1-one, 4,5-dihydroxy-2-(1E)-1-propenyl-, (4R,5S)-rel-; Dihydroxypropenylcyclopentenone; Chiral Dihydroxycyclopentenone Derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopenten-1-One,4,5-Dihydroxy-2-(1E)-1-Propenyl-,(4R,5S)-Rel-(9Ci) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and compliance with customer specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (rel-(4R,5S)-)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.