Description

3-Benzyl-4,8-Dimethyl-7-[2-Nitro-4-(Trifluoromethyl)Phenoxy]Chromen-2-One is a specialized synthetic organic compound belonging to the chromen-2-one (coumarin) class, distinguished by its benzyl and trifluoromethylphenoxy substituents. This compound is valued for its role as a key synthetic intermediate or a potential pharmacophore in advanced research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active ingredients. The structural complexity of this molecule makes it a critical component for studies in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold or pharmacophore for structure-activity relationship (SAR) studies and biological screening.
• Agrochemical Development: Investigated as a potential intermediate for creating new crop protection agents with specific modes of action.
• Material Science Precursor: Explored for the development of advanced organic materials, including dyes, pigments, or optical materials.
• Biochemical Probe Synthesis: Utilized in constructing molecular probes for studying enzyme inhibition or cellular pathways.
• Academic & Contract Research: Employed in university and CRO settings for fundamental organic synthesis and methodological research.

Basic Information

Item	Details
Product Name	3-Benzyl-4,8-Dimethyl-7-[2-Nitro-4-(Trifluoromethyl)Phenoxy]Chromen-2-One
CAS No.	376612-69-0
Molecular Formula	C25H18F3NO5
Molecular Weight	469.41 g/mol
Synonyms	3-Benzyl-4,8-dimethyl-7-[2-nitro-4-(trifluoromethyl)phenoxy]-2H-chromen-2-one; 3-Benzyl-4,8-dimethyl-7-[2-nitro-4-(trifluoromethyl)phenoxy]coumarin; 7-[2-Nitro-4-(trifluoromethyl)phenoxy]-3-benzyl-4,8-dimethylchromen-2-one; 2H-1-Benzopyran-2-one, 3-benzyl-4,8-dimethyl-7-[2-nitro-4-(trifluoromethyl)phenoxy]-; 376612-69-0; Coumarin derivative with benzyl and trifluoromethylphenoxy groups.
EINECS	Contact for details

Quality Control

Our 3-Benzyl-4,8-Dimethyl-7-[2-Nitro-4-(Trifluoromethyl)Phenoxy]Chromen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.