Description

Glycine, N-[2-(2-Hydroxyethoxy)ethyl]- (9CI) is a specialized, high-purity derivative of the amino acid glycine, featuring a hydrophilic polyether side chain. This unique structure makes it a valuable versatile building block and functional intermediate for advanced chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel compounds, linkers, and surface-active agents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), prodrugs, and diagnostic agents, where its hydrophilic spacer can enhance solubility and pharmacokinetics.
• Bioconjugation & Linker Chemistry: Serves as a key component in creating peptide mimetics, antibody-drug conjugates (ADCs), and polymer-drug conjugates due to its bifunctional nature.
• Surface Modification Agent: Employed to functionalize nanoparticles, polymers, and biomaterial surfaces to improve hydrophilicity, biocompatibility, and specific binding properties.
• Specialty Surfactant & Emulsifier Precursor: Acts as a raw material for synthesizing novel, mild surfactants for personal care, cosmetic, and agrochemical formulations.
• Cross-linking Agent: Utilized in the production of hydrogels, resins, and advanced polymeric materials requiring controlled cross-linking density.
• Research & Development: A critical reagent in academic and industrial research for exploring new chemical entities and material science applications.

Basic Information

Product Name	Glycine, N-[2-(2-Hydroxyethoxy)ethyl]- (9CI)
CAS No.	375387-79-4
Molecular Formula	C6H13NO4
Molecular Weight	163.17 g/mol
Synonyms	2-[2-(2-Hydroxyethoxy)ethoxy]ethylamine, N-(Carboxymethyl); 2,2'-(Ethylenedioxy)di(ethanamine), N-Carboxymethyl-; N-Carboxymethyl-2,2'-(ethylenedioxy)diethanamine; Diglycolamine, N-Carboxymethyl-; Amino-PEG2-acetic acid; H2N-PEG2-CH2COOH; N-(2-(2-(2-Hydroxyethoxy)ethoxy)ethyl)glycine; Glycine, N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]-
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.