Description

(4R,5R)-1,3-Bis(2-Isopropylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate CAS NO 372517-14-1 is a high-purity, chiral imidazolium salt primarily utilized as a specialized catalyst precursor or ligand in advanced organic synthesis. This compound matters for its role in facilitating highly selective and efficient asymmetric transformations, which are critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical manufacturing. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: Serving as a precursor for chiral N-heterocyclic carbene (NHC) ligands in transition metal-catalyzed reactions like cross-coupling, hydrogenation, and olefin metathesis.
• Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of complex molecular architectures for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Material Science: Potential application in the synthesis of chiral ionic liquids or functional polymers with specific optical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process optimization studies.
• Fine Chemical Production: For the manufacture of high-value, enantiomerically pure flavors, fragrances, and other specialty chemicals.

Basic Information

Product Name	(4R,5R)-1,3-Bis(2-Isopropylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate
CAS No.	372517-14-1
Molecular Formula	C33H33BF4N2
Molecular Weight	544.44 g/mol
Synonyms	(4R,5R)-1,3-Bis(2-Isopropylphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; (R,R)-1,3-Bis(2-isopropylphenyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-3-ium tetrafluoroborate; Chiral Imidazolium Tetrafluoroborate Salt; NHC Precursor Salt; (R,R)-IPr*·HBF4; (4R,5R)-IMes·HBF4 analogue; 1,3-Bis(2-Isopropylphenyl)imidazolinium Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our (4R,5R)-1,3-Bis(2-Isopropylphenyl)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-3-Ium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.