Description

8-[(Diethylamino)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One is a sophisticated chromen-4-one derivative, a key chemical building block valued for its unique structural features. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate complex, functionalized chromene scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the chromen-4-one core is pharmacologically active.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its complex structure for enhanced biological activity and selectivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a potential building block for electron-transport or emissive layer materials in OLED displays and lighting due to its conjugated system and functional groups.
• Fluorescent Probe & Dye Synthesis: The chromene and naphthyloxy components make it a candidate for synthesizing advanced fluorescent markers and dyes for bio-imaging and analytical applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel coupling reactions and heterocyclic compound synthesis.
• Coordination Chemistry & Ligand Design: The hydroxyl and amino groups provide potential binding sites for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	8-[(Diethylamino)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One
CAS No.	371218-98-3
Molecular Formula	C25H22F3NO4
Molecular Weight	457.44 g/mol
Synonyms	7-Hydroxy-8-[(diethylamino)methyl]-3-(2-naphthyloxy)-2-(trifluoromethyl)-4H-chromen-4-one; 2-(Trifluoromethyl)-3-(naphthalen-2-yloxy)-7-hydroxy-8-[(diethylamino)methyl]chromen-4-one; 4H-1-Benzopyran-4-one, 8-[(diethylamino)methyl]-7-hydroxy-3-(2-naphthalenyloxy)-2-(trifluoromethyl)-; Chromen-4-one derivative CAS 371218-98-3
EINECS	Contact for details

Quality Control

Our production of 8-[(Diethylamino)Methyl]-7-Hydroxy-3-(2-Naphthyloxy)-2-(Trifluoromethyl)-4H-Chromen-4-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.