Description

Cyclopentanecarboxylic Acid, 1-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci) is a high-purity, multifunctional chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, offering a rigid cyclopentane scaffold with protected amine and hydroxyl functionalities. Pharmaceutical research and development organizations, particularly those focused on medicinal chemistry and process development for new drug candidates, are the primary users of this specialized chemical.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to construct conformationally constrained peptide analogs, enhancing metabolic stability and receptor selectivity.
• Protease Inhibitor Development: Acts as a core scaffold in the design and synthesis of inhibitors for various protease enzymes.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the cyclopentane moiety with defined stereochemistry into more complex molecular architectures.
• Chemical Biology Probes: Utilized in the creation of specialized molecular tools for studying enzyme function and cellular pathways.
• Agrochemical Research: Functions as an intermediate in the development of new generation herbicides or fungicides with specific modes of action.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci)
CAS No.	369403-15-6
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-[(tert-Butoxycarbonyl)amino]-3-hydroxycyclopentanecarboxylic acid; (1R,3S)-1-[(tert-Butoxycarbonyl)amino]-3-hydroxycyclopentanecarboxylic acid (for specific enantiomer); 1-(Boc-amino)-3-hydroxycyclopentanecarboxylic acid; 3-Hydroxy-1-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid; Boc-3-Hydroxy-cyclopentane-1-carboxylic acid; 1-N-Boc-amino-3-hydroxy-cyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-
EINECS	Contact for details

Quality Control

Every batch of Cyclopentanecarboxylic Acid, 1-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chiral purity analysis and impurity profiling, to ensure compliance with the stringent standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (enantiomer specified)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual unknown ≤0.10%, Total ≤0.50%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.