Description

(S)-Amino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester is a high-purity chiral building block essential for modern pharmaceutical synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly for complex, stereoselective drug candidates. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the production of enantiomerically pure molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetics: Serves as a constrained, non-natural amino acid analog in the design of peptide-based drugs and diagnostic agents.
• Asymmetric Synthesis: Employed as a versatile building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and molecular probes for studying biological pathways.

Basic Information

Product Name	(S)-Amino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester
CAS No.	368866-32-4
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid methyl ester; Methyl (S)-2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate; (S)-2-(Tetrahydro-2H-pyran-4-yl)glycine methyl ester; (S)-Amino(oxan-4-yl)acetic acid methyl ester; (S)-Methyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate; L-2-(Tetrahydro-2H-pyran-4-yl)glycine methyl ester; (S)-2-(Oxan-4-yl)glycine methyl ester
EINECS	Contact for details

Quality Control

Our (S)-Amino-(Tetrahydro-Pyran-4-Yl)-Acetic Acid Methyl Ester is manufactured under strict quality systems suitable for pharmaceutical R&D and scale-up. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure consistent quality and enantiomeric excess. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.