Description

3-[3-(Trifluoromethyl)Phenyl]Phenol is a high-value fluorinated phenolic compound characterized by its trifluoromethyl-substituted aromatic structure. This compound serves as a versatile and critical advanced pharmaceutical intermediate and organic synthesis building block, enabling the introduction of lipophilic and electron-withdrawing groups into target molecules. It is essential for R&D and production in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the production of high-performance liquid crystals for display technologies.
• Polymer & Material Science: Incorporated as a monomer or additive to create specialty polymers with enhanced thermal stability, chemical resistance, and unique optical properties.
• Organic Electronic Materials: Utilized in the research and development of organic light-emitting diodes (OLEDs) and semiconductor materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and exploratory synthesis in academic and industrial laboratories.

Basic Information

Product Name	3-[3-(Trifluoromethyl)Phenyl]Phenol
CAS No.	365426-92-2
Molecular Formula	C13H9F3O
Molecular Weight	238.21 g/mol
Synonyms	3'-(Trifluoromethyl)[1,1'-biphenyl]-3-ol; [1,1'-Biphenyl]-3-ol, 3'-(trifluoromethyl)-; 3-(3-Trifluoromethylphenyl)phenol; m-(3-Trifluoromethylphenyl)phenol; 3-Hydroxy-3'-(trifluoromethyl)biphenyl; 3-(3-Trifluoromethyl-phenyl)-phenol
EINECS	Contact for details

Quality Control

Our 3-[3-(Trifluoromethyl)Phenyl]Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ISO standards for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.