Description

6-Amino-4-{2-[(2-Chlorobenzyl)Oxy]-4-Methoxyphenyl}-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyranopyrazole class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for applications in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries to screen for biological activity against various disease targets.
• Oncology Drug Development: Employed in the research and development of potential anti-cancer agents due to its complex heterocyclic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and scale-up services.
• Academic Research: Used in university and institutional labs for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	6-Amino-4-{2-[(2-Chlorobenzyl)Oxy]-4-Methoxyphenyl}-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	364744-00-3
Molecular Formula	C22H19ClN4O3
Molecular Weight	422.86 g/mol
Synonyms	6-Amino-4-(2-((2-chlorobenzyl)oxy)-4-methoxyphenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-methyl-4-[2-[(2-chlorophenyl)methoxy]-4-methoxyphenyl]-1,4-dihydro-2H-pyrano[2,3-c]pyrazole-5-carbonitrile; 364744-00-3; Dihydropyrano[2,3-c]pyrazole-5-carbonitrile derivative; 4-(2-((2-Chlorobenzyl)oxy)-4-methoxyphenyl)-6-amino-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Amino-4-{2-[(2-Chlorobenzyl)Oxy]-4-Methoxyphenyl}-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided to ensure traceability and compliance with your research or cGMP guidelines for early-phase development. Our quality commitment ensures material consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.