Description

3-Pyridazinecarboxylic Acid, Hexahydro-5-Hydroxy-, (3R,5R)- (9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is valued for its defined stereochemistry and functional groups, which are critical for synthesizing complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct complex molecular frameworks.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for designing and screening new drug candidates.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for target molecules in clinical development.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic applications.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis and chemical biology.

Basic Information

Product Name	3-Pyridazinecarboxylic Acid, Hexahydro-5-Hydroxy-, (3R,5R)- (9Ci)
CAS No.	364070-92-8
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(3R,5R)-Hexahydro-5-hydroxy-3-pyridazinecarboxylic acid; (3R,5R)-5-Hydroxyhexahydro-3-pyridazinecarboxylic acid; (3R,5R)-5-Hydroxypiperidine-3-carboxylic acid (tautomeric form); 3-Pyridazinecarboxylic acid, hexahydro-5-hydroxy-, (3R,5R)-; (3R,5R)-5-Hydroxy-1,2,3,4,5,6-hexahydro-3-pyridazinecarboxylic acid; (3R,5R)-5-Hydroxy-3-piperidinecarboxylic acid; (3R,5R)-5-Hydroxypipecolic acid (common name for the piperidinecarboxylic acid form); CAS 364070-92-8.
EINECS	Contact for details

Quality Control

Our 3-Pyridazinecarboxylic Acid, Hexahydro-5-Hydroxy-, (3R,5R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and critical impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,5R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.