Description

2-Amino-n-Cyclobutyl-Acetamide is a specialized organic compound featuring both amino and acetamide functional groups on a cyclobutyl scaffold, making it a valuable building block in synthetic chemistry. This unique structure is critical for the development of novel pharmacologically active molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or as enzyme inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Acts as a constrained, non-natural amino acid analog for creating peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and development of new pesticides and herbicides, leveraging its bioactive amine functionality.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) serving the life sciences industry.

Basic Information

Product Name	2-Amino-n-Cyclobutyl-Acetamide
CAS No.	359821-39-9
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	2-Amino-N-cyclobutylacetamide; Cyclobutylglycinamide; α-Amino-N-cyclobutylacetamide; 2-Amino-2-cyclobutylacetamide; Acetamide, 2-amino-N-cyclobutyl-; (Aminomethyl)cyclobutylmethanamide; Glycinamide, N-cyclobutyl-
EINECS	Contact for details

Quality Control

Our 2-Amino-n-Cyclobutyl-Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each batch, detailing specifications for assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.