Description

(Cyclohexylmethyl)(1-Phenylethyl)Amine CAS NO 356540-15-3 is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of pharmaceutically active molecules, particularly those requiring specific stereochemistry. It is primarily needed by research and development chemists and process development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for developing novel chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Agrochemical Research: Used in the development of new chiral herbicides, fungicides, and plant growth regulators where stereochemistry impacts biological activity.
• Fine Chemical Synthesis: Employed in multi-step syntheses of complex natural products, flavors, and fragrances requiring amine functionality with specific stereocenters.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including new amination and C-N bond-forming reactions.

Basic Information

Product Name	(Cyclohexylmethyl)(1-Phenylethyl)Amine
CAS No.	356540-15-3
Molecular Formula	C15H23N
Molecular Weight	217.35 g/mol
Synonyms	N-[(1S)-1-Phenylethyl]-1-cyclohexanemethanamine; N-[(1R)-1-Phenylethyl]-1-cyclohexanemethanamine; 1-Cyclohexyl-N-[(1-phenylethyl)]methanamine; α-Methylbenzylcyclohexylmethylamine; (1-Phenylethyl)(cyclohexylmethyl)amine; Cyclohexylmethyl(1-phenylethyl)amine; (Cyclohexylmethyl)(α-methylbenzyl)amine
EINECS	Contact for details

Quality Control

Our (Cyclohexylmethyl)(1-Phenylethyl)Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee (enantiomer excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.