Description

n-(4,6-Dimethylpyrimidin-2-Yl)-3,4-Dihydroquinoline-1(2H)-Carboximidamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of investigational new drugs and specialty APIs.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs targeting various diseases.
• Process Development & Scale-up: Employed in optimizing synthetic routes from laboratory to pilot and commercial-scale production.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	n-(4,6-Dimethylpyrimidin-2-Yl)-3,4-Dihydroquinoline-1(2H)-Carboximidamide
CAS No.	355824-85-0
Molecular Formula	C₁₆H₁₉N₅
Molecular Weight	281.36 g/mol
Synonyms	1(2H)-Quinolinecarboximidamide, N-(4,6-dimethyl-2-pyrimidinyl)-3,4-dihydro-; 3,4-Dihydro-N-(4,6-dimethyl-2-pyrimidinyl)-1(2H)-quinolinecarboximidamide; 1,2,3,4-Tetrahydro-N-(4,6-dimethyl-2-pyrimidinyl)-1-quinolinecarboximidamide; Carboximidamide, N-(4,6-dimethyl-2-pyrimidinyl)-3,4-dihydro-2H-quinoline-1-; CAS 355824-85-0
EINECS	Contact for details

Quality Control

Our n-(4,6-Dimethylpyrimidin-2-Yl)-3,4-Dihydroquinoline-1(2H)-Carboximidamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.