Description

Dansylamidoethyl Methanethiosulfonate is a specialized, high-purity chemical reagent designed for advanced bioconjugation and protein labeling applications. This compound matters for researchers and manufacturers who require precise, site-specific modification of biomolecules, particularly thiol groups, for analytical and diagnostic purposes. It is primarily needed by professionals in pharmaceutical R&D, biotechnology, and academic research for developing assays, probes, and therapeutic conjugates.

Application

• Site-Specific Protein Labeling: Selective modification of cysteine residues in proteins and antibodies for fluorescence tagging.
• Bioconjugation Reagent: Used to attach dansyl fluorophores or other functional groups to peptides, enzymes, and other biomolecules.
• Proteomics Research: A key tool for studying protein structure, function, and interactions via fluorescence-based detection methods.
• Diagnostic Assay Development: Employed in the synthesis of fluorescent probes and reagents for immunoassays and biosensors.
• Chemical Biology Tool: Facilitates the study of thiol reactivity and dynamics in living cells and complex biological systems.
• Pharmaceutical Analysis: Used in method development for the analysis and characterization of biopharmaceuticals.

Basic Information

Product Name	Dansylamidoethyl Methanethiosulfonate
CAS No.	355115-41-2
Molecular Formula	C15H20N2O4S2
Molecular Weight	356.46 g/mol
Synonyms	5-((2-((Methylsulfonyl)thio)ethyl)amino)-N-(5-(dimethylamino)naphthalen-1-yl)sulfonyl)naphthalene-1-sulfonamide; Dansyl Ethyl Methanethiosulfonate; MTS-Dansyl; Dansylamidoethyl MTS; N-[2-[(Methylsulfonyl)thio]ethyl]-5-(dimethylamino)-1-naphthalenesulfonamide; Dansyl C2 MTS Reagent; Thiol-reactive dansyl probe
EINECS	Contact for details

Quality Control

Our Dansylamidoethyl Methanethiosulfonate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.