Description

6-Amino-3-tert-Butyl-4-(3,4-Dimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for applications in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Oncology Drug Development: A potential scaffold for developing kinase inhibitors and other anti-cancer agents.
• CNS Drug Discovery: Employed in research for neurological and psychiatric disorder treatments.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Used in universities and institutes for heterocyclic chemistry and synthetic methodology studies.

Basic Information

Product Name	6-Amino-3-tert-Butyl-4-(3,4-Dimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	354554-31-7
Molecular Formula	C19H22N4O3
Molecular Weight	354.41 g/mol
Synonyms	6-Amino-3-tert-butyl-4-(3,4-dimethoxyphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-(tert-butyl)-4-(3,4-dimethoxyphenyl)-1,4-dihydro-5H-pyrano[2,3-c]pyrazole-5-carbonitrile; 354554-31-7; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-3-(1,1-dimethylethyl)-4-(3,4-dimethoxyphenyl)-1,4-dihydro-; 6-Amino-3-tert-butyl-4-(3,4-dimethoxyphenyl)-1,4-dihydro-5H-pyrano[2,3-c]pyrazole-5-carbonitrile; 1,4-Dihydropyrano[2,3-c]pyrazole-5-carbonitrile derivative; Fused pyranopyrazole intermediate
EINECS	Contact for details

Quality Control

Our 6-Amino-3-tert-Butyl-4-(3,4-Dimethoxyphenyl)-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.