Description

6-Amino-4-{4-Methoxy-3-[(2-Pyridinylsulfanyl)Methyl]Phenyl}-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyrano[2,3-c]pyrazole class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses due to its reactive amino and nitrile functional groups within a fused heterocyclic framework.
• Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.
• Academic Research: Used in university and institutional labs for exploratory research in heterocyclic and pharmaceutical chemistry.

Basic Information

Item	Details
Product Name	6-Amino-4-{4-Methoxy-3-[(2-Pyridinylsulfanyl)Methyl]Phenyl}-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	354550-65-5
Molecular Formula	C21H19N5O2S
Molecular Weight	405.47 g/mol
Synonyms	6-Amino-3-methyl-4-[4-methoxy-3-[(pyridin-2-ylsulfanyl)methyl]phenyl]-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 6-Amino-3-methyl-4-(4-methoxy-3-((pyridin-2-ylthio)methyl)phenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 354550-65-5; Dihydropyranopyrazole carbonitrile derivative; CAS 354550-65-5
EINECS	Contact for details

Quality Control

Our 6-Amino-4-{4-Methoxy-3-[(2-Pyridinylsulfanyl)Methyl]Phenyl}-3-Methyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.