Description

2-Amino-4-[5-(4-Chloro-Phenyl)-Furan-2-Yl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-purity, complex heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and research chemical. Its intricate molecular structure, featuring chromene, furan, and nitrile functional groups, makes it a valuable scaffold for the synthesis of novel bioactive molecules. This compound is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Fine Chemical Production: Intermediate for manufacturing specialized dyes, pigments, or functional materials requiring complex chromophore systems.
• Academic & Institutional Research: Utilized in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.

Basic Information

Product Name	2-Amino-4-[5-(4-Chloro-Phenyl)-Furan-2-Yl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	353466-95-2
Molecular Formula	C22H19ClN2O3
Molecular Weight	394.85 g/mol
Synonyms	2-Amino-4-(5-(4-chlorophenyl)furan-2-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-[5-(4-chlorophenyl)-2-furanyl]-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; Chromene-carbonitrile derivative (CAS 353466-95-2); Tetrahydrochromene nitrile intermediate; 4-(5-(4-Chlorophenyl)furan-2-yl)-2-amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-[5-(4-Chloro-Phenyl)-Furan-2-Yl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.