Description

6-Amino-4-[5-Chloro-3-Methyl-1-(4-Methylphenyl)-1H-Pyrazol-4-Yl]-3-Propyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with the CAS number 351522-71-9. This compound is a key synthetic building block valued for its complex heterocyclic structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used as a key scaffold for developing new-generation pesticides and herbicides with specific modes of action.
• Chemical Synthesis: Serves as a versatile building block for constructing complex fused pyrazole and pyranopyrazole derivatives in medicinal chemistry.
• R&D Laboratories: Employed in academic and industrial research for studying structure-activity relationships (SAR) and discovering new bioactive molecules.
• API Manufacturing: Integrated into the production process of target active pharmaceutical ingredients requiring this specific molecular framework.

Basic Information

Product Name	6-Amino-4-[5-Chloro-3-Methyl-1-(4-Methylphenyl)-1H-Pyrazol-4-Yl]-3-Propyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	351522-71-9
Molecular Formula	C₂₃H₂₃ClN₆O
Molecular Weight	434.92 g/mol
Synonyms	6-Amino-4-(5-chloro-3-methyl-1-p-tolyl-1H-pyrazol-4-yl)-3-propyl-2,4-dihydro-5-cyanopyrano[2,3-c]pyrazole; 6-Amino-4-(5-chloro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl)-3-propyl-2,4-dihydro-5-cyanopyrano[2,3-c]pyrazole; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-[5-chloro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-4-yl]-2,4-dihydro-3-propyl-; CAS 351522-71-9
EINECS	Contact for details

Quality Control

Our 6-Amino-4-[5-Chloro-3-Methyl-1-(4-Methylphenyl)-1H-Pyrazol-4-Yl]-3-Propyl-2,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our production adheres to cGMP standards where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.