Description

2-Acetylthio-3'-Nitroacetophenone is a high-purity organic building block characterized by its distinct acetylthio and nitro functional groups. This compound matters as a versatile and critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds and functionalized aromatic systems.
• Material Science Precursor: Investigated for the preparation of specialized polymers or organic electronic materials due to its electron-withdrawing nitro group.
• Bioconjugation Chemistry: The acetylthio group can be utilized in thiol-based coupling reactions for labeling or modifying biomolecules.
• Academic & R&D: A valuable reagent for methodological studies and exploring new chemical reactions in university and industrial research laboratories.

Basic Information

Product Name	2-Acetylthio-3'-Nitroacetophenone
CAS No.	351003-16-2
Molecular Formula	C10H9NO4S
Molecular Weight	239.25 g/mol
Synonyms	1-(3-Nitrophenyl)-2-(acetylthio)ethanone; 2-(Acetylsulfanyl)-1-(3-nitrophenyl)ethanone; 3'-Nitro-2-acetylthioacetophenone; Ethanone, 2-(acetylthio)-1-(3-nitrophenyl)-; 2-Acetylthio-3-nitroacetophenone; 2-(Acetylthio)-3'-nitroacetophenone
EINECS	Contact for details

Quality Control

Our 2-Acetylthio-3'-Nitroacetophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure a typical purity of 97% or higher and confirm identity and consistency. Certificates of Analysis (COA) detailing purity, impurities, and physical data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.