Description

Trifluoro-Methanesulfonic Acid 2-Morpholin-4-Yl-4-Oxo-4H-Chromen-8-Yl Ester is a high-value, multifunctional chemical building block that combines a chromone core with a reactive triflate ester group. This compound is critical for advanced organic synthesis, enabling efficient cross-coupling reactions and the introduction of complex pharmacophores. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other chromone-based therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the chromone scaffold can impart specific biological activity.
• Material Science: Serves as a precursor for advanced organic materials, such as organic semiconductors or fluorescent dyes, leveraging its conjugated chromone system.
• Cross-Coupling Reactions: The triflate ester group acts as an excellent leaving group in palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Academic & Contract Research: Essential reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).

Basic Information

Product Name	Trifluoro-Methanesulfonic Acid 2-Morpholin-4-Yl-4-Oxo-4H-Chromen-8-Yl Ester
CAS No.	351002-11-4
Molecular Formula	C₁₈H₁₆F₃NO₆S
Molecular Weight	431.38 g/mol
Synonyms	8-(Trifluoromethanesulfonyloxy)-2-morpholino-4H-chromen-4-one; 2-Morpholino-4-oxo-4H-chromen-8-yl trifluoromethanesulfonate; 2-Morpholin-4-yl-4-oxo-4H-chromen-8-yl triflate; Trifluoromethanesulfonic acid 2-morpholino-4-oxo-4H-chromen-8-yl ester; 8-Triflyloxy-2-morpholinochromone; CAS 351002-11-4
EINECS	Contact for details

Quality Control

Every batch of Trifluoro-Methanesulfonic Acid 2-Morpholin-4-Yl-4-Oxo-4H-Chromen-8-Yl Ester is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to strict internal quality standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.