Description

[5-(1,3-Dioxolan-2-Yl)Thiophen-2-Yl]Tributylstannane CAS NO 349616-56-4 is a specialized organotin compound featuring a protected aldehyde functionality, making it a valuable intermediate in advanced organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex heterocyclic and conjugated molecular architectures. This high-purity reagent is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science sectors who require reliable building blocks for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing thiophene and dioxolane motifs for targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the organotin moiety facilitates efficient cross-coupling reactions.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for creating electron-transport or emissive layers in display and lighting technologies.
• Polymer Chemistry: Employed as a monomer or chain-transfer agent in the synthesis of specialty polymers with tailored electronic properties.
• Cross-Coupling Reactions (Stille Coupling): Acts as a versatile stannane reagent for palladium-catalyzed coupling with aryl or vinyl halides, constructing complex biaryl systems.
• Chemical Research & Development: A critical tool for academic and industrial R&D labs exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	[5-(1,3-Dioxolan-2-Yl)Thiophen-2-Yl]Tributylstannane
CAS No.	349616-56-4
Molecular Formula	C19H34O2SSn
Molecular Weight	445.22 g/mol
Synonyms	2-(5-(Tributylstannyl)thiophen-2-yl)-1,3-dioxolane; Tributyl(5-(1,3-dioxolan-2-yl)thiophen-2-yl)stannane; 5-(1,3-Dioxolan-2-yl)-2-(tributylstannyl)thiophene; 2-Thienylstannane, 5-(1,3-dioxolan-2-yl)-, tributyl-; Stannane, tributyl[5-(1,3-dioxolan-2-yl)-2-thienyl]-; [5-(1,3-Dioxolan-2-yl)-2-thienyl]tributylstannane; Tributyl(5-(2,2-dimethyl-1,3-dioxolan-4-yl)thiophen-2-yl)stannane (related protected form)
EINECS	Contact for details

Quality Control

Our [5-(1,3-Dioxolan-2-Yl)Thiophen-2-Yl]Tributylstannane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive cross-coupling reactions. Each lot undergoes comprehensive analytical characterization including NMR (1H, 13C), HPLC, and elemental analysis to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maintain stability and prevent degradation. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin (Sn) Content	26.5 - 27.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.