Description

2-[(2-Chlorophenyl)Amino]-N'-[(E)-(3-Hydroxyphenyl)Methylidene]Acetohydrazide is a specialized organic compound belonging to the class of acetohydrazide derivatives, which are of significant interest in advanced chemical synthesis. This compound serves as a crucial pharmacophore and versatile synthetic intermediate for developing novel molecules with targeted biological activities. It is primarily needed by pharmaceutical R&D laboratories, agrochemical research facilities, and fine chemical manufacturers engaged in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive hydrazide core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and protein-ligand interactions.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers, ligands for metal complexes, and organic electronic materials.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2-[(2-Chlorophenyl)Amino]-N'-[(E)-(3-Hydroxyphenyl)Methylidene]Acetohydrazide (Non-Preferred Name)
CAS No.	349462-97-1
Molecular Formula	C15H14ClN3O2
Molecular Weight	303.74 g/mol
Synonyms	N'-(3-Hydroxybenzylidene)-2-[(2-chlorophenyl)amino]acetohydrazide; (E)-N'-(3-Hydroxybenzylidene)-2-((2-chlorophenyl)amino)acetohydrazide; 2-(2-Chloroanilino)-N-[(E)-(3-hydroxyphenyl)methylidene]acetohydrazide; Acetohydrazide, 2-[(2-chlorophenyl)amino]-N'-[(E)-(3-hydroxyphenyl)methylene]-; 349462-97-1; 2-(2-Chlorophenylamino)-N'-(3-hydroxybenzylidene)acetohydrazide
EINECS	Contact for details

Quality Control

Our production of 2-[(2-Chlorophenyl)Amino]-N'-[(E)-(3-Hydroxyphenyl)Methylidene]Acetohydrazide adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and elemental analysis for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. Our quality system is designed to support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.