Description

1H-Imidazole, 1-(Dichloroacetyl)-4,5-Dihydro-2-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a versatile synthon for creating complex heterocyclic compounds used in material science and specialty chemistry.
• Biochemical Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	1H-Imidazole, 1-(Dichloroacetyl)-4,5-Dihydro-2-Methyl- (9Ci)
CAS No.	349142-57-0
Molecular Formula	C7H8Cl2N2O
Molecular Weight	207.05 g/mol
Synonyms	1-(Dichloroacetyl)-4,5-dihydro-2-methyl-1H-imidazole; 2-Methyl-4,5-dihydro-1H-imidazole, 1-(dichloroacetyl)-; 1-(Dichloroacetyl)-2-methyl-4,5-dihydroimidazole; 1-(Dichloroacetyl)-2-methyl-2-imidazoline; 2-Methyl-1-(dichloroacetyl)-2-imidazoline; 1H-Imidazole, 1-(dichloroacetyl)-4,5-dihydro-2-methyl-; 349142-57-0
EINECS	Contact for details

Quality Control

Our 1H-Imidazole, 1-(Dichloroacetyl)-4,5-Dihydro-2-Methyl- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.