Description

4,5-Pyridazinediol, Hexahydro-3-(Hydroxymethyl)-, (3R,4S,5R)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its unique functional group array, making it a versatile intermediate for constructing complex molecular architectures with precise stereochemical control. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and neurological drug candidates.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable tool for methodological studies in synthetic organic chemistry and medicinal chemistry programs.
• Bioconjugate Chemistry: Potential use in developing linkers or payloads for antibody-drug conjugates (ADCs) due to its functionalizable hydroxyl groups.

Basic Information

Product Name	4,5-Pyridazinediol, Hexahydro-3-(Hydroxymethyl)-, (3R,4S,5R)- (9Ci)
CAS No.	349108-45-8
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	(3R,4S,5R)-Hexahydro-3-(hydroxymethyl)-4,5-pyridazinediol; Hexahydro-3-(hydroxymethyl)-4,5-pyridazinediol, (3R,4S,5R)-; (3R,4S,5R)-3-(Hydroxymethyl)hexahydro-4,5-pyridazinediol; 1,2-Diazinane-3,4,5-triol, 3-(hydroxymethyl)-, (3R,4S,5R)-; Stereoisomer of a pyridazine-diol derivative; Chiral hexahydropyridazinediol.
EINECS	Contact for details

Quality Control

Every batch of 4,5-Pyridazinediol, Hexahydro-3-(Hydroxymethyl)-, (3R,4S,5R)- (9Ci) is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and stereochemical integrity. Our standard grade meets high-purity research specifications, with Certificates of Analysis (COA) provided for each lot, detailing assay, chiral purity, and impurity profiles. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (3R,4S,5R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.