Description

1-Butanamine,3-Methyl-4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-(9Ci) is a specialized amine derivative featuring a protected hydroxyl group, making it a valuable chiral building block and synthetic intermediate. This compound matters for its role in facilitating complex organic syntheses, particularly in the development of pharmaceuticals and agrochemicals where precise stereochemistry is critical. It is primarily needed by research chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing advanced molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or with complex stereocenters.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific amine-based functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands used in asymmetric catalysis to induce high enantioselectivity in reactions.
• Fine Chemical Synthesis: Employed in custom and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic and R&D Laboratories: Utilized in methodological research and for exploring new synthetic pathways in organic chemistry.
• Peptidomimetic Chemistry: Acts as a building block for non-natural amino acids or peptide analogs in drug discovery programs.

Basic Information

Product Name	1-Butanamine,3-Methyl-4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-(9Ci)
CAS No.	348078-76-2
Molecular Formula	C10H21NO2
Molecular Weight	187.28 g/mol
Synonyms	3-Methyl-4-[(tetrahydro-2H-pyran-2-yl)oxy]-1-butanamine; 4-(Tetrahydro-2H-pyran-2-yloxy)-3-methylbutylamine; 3-Methyl-4-(tetrahydropyran-2-yloxy)butan-1-amine; THP-protected 3-methyl-4-aminobutanol; 4-Amino-2-methylbutyl tetrahydro-2H-pyran-2-yl ether; (3-Methyl-4-((tetrahydro-2H-pyran-2-yl)oxy)butyl)amine
EINECS	Contact for details

Quality Control

Our 1-Butanamine,3-Methyl-4-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.