Description

2-Amino-4-(2,4-Dichlorophenyl)-4H-Benzo[H]Chromene-3-Carbonitrile is a high-value, multi-functional heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique chromene core structure, functionalized with amino and nitrile groups, makes it an essential intermediate for developing novel pharmaceuticals and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating libraries of new chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a monomer or precursor for synthesizing specialty polymers, dyes, and photoactive materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and as a scaffold for combinatorial chemistry to explore structure-activity relationships (SAR).
• Chemical Biology: Utilized as a probe or tag in biochemical assays due to its fluorescent chromene core.

Basic Information

Product Name	2-Amino-4-(2,4-Dichlorophenyl)-4H-Benzo[H]Chromene-3-Carbonitrile
CAS No.	346436-68-8
Molecular Formula	C20H12Cl2N2O
Molecular Weight	367.23 g/mol
Synonyms	2-Amino-4-(2,4-dichlorophenyl)-4H-benzo[h]chromene-3-carbonitrile; 4H-Benzo[h]chromene-3-carbonitrile, 2-amino-4-(2,4-dichlorophenyl)-; 2-Amino-4-(2,4-dichlorophenyl)-4H-1-benzopyran-3-carbonitrile; 2-Amino-4-(2,4-dichlorophenyl)-4H-chromene-3-carbonitrile; Benzo[h]chromene derivative CAS 346436-68-8
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-(2,4-Dichlorophenyl)-4H-Benzo[H]Chromene-3-Carbonitrile adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.