Description

1-[(4-Ethylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid is a high-purity sulfonamide derivative and a versatile synthetic building block of significant interest in advanced organic synthesis. Its unique molecular structure, featuring both a sulfonyl and a carboxylic acid functional group on a piperidine scaffold, makes it a critical intermediate for the development of novel pharmacologically active compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its sulfonamide chemistry.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Ligand and Catalyst Development: The carboxylic acid and sulfonyl groups make it a potential precursor for designing novel chelating agents or organocatalysts.

Basic Information

Product Name	1-[(4-Ethylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid
CAS No.	345990-55-8
Molecular Formula	C14H19NO4S
Molecular Weight	297.37 g/mol
Synonyms	4-Carboxy-1-[(4-ethylphenyl)sulfonyl]piperidine; 1-(4-Ethylbenzenesulfonyl)piperidine-4-carboxylic Acid; Piperidine-4-carboxylic acid, 1-[(4-ethylphenyl)sulfonyl]-; 4-(4-Ethylphenylsulfonyl)piperidine-1-carboxylic Acid (tautomer); 345990-55-8; 1-(p-Ethylphenylsulfonyl)isonipecotic Acid
EINECS	Contact for details

Quality Control

Our 1-[(4-Ethylphenyl)Sulfonyl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality assurance ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.