Description

(E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Fluorophenyl)-2-Propen-1-One n-(4-Fluorophenyl)Hydrazone is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated hydrazone structure enables precise molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in research to create molecular tools for studying enzyme inhibition and receptor-ligand interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Fluorophenyl)-2-Propen-1-One n-(4-Fluorophenyl)Hydrazone
CAS No.	343374-70-9
Molecular Formula	C21H14ClF2N2O
Molecular Weight	386.80 g/mol
Synonyms	(E)-3-(2-Chloro-6-fluorophenyl)-1-(4-fluorophenyl)-2-propen-1-one (4-fluorophenyl)hydrazone; (E)-1-(4-Fluorophenyl)-3-(2-chloro-6-fluorophenyl)-2-propen-1-one N-(4-fluorophenyl)hydrazone; 2-Propen-1-one, 3-(2-chloro-6-fluorophenyl)-1-(4-fluorophenyl)-, (4-fluorophenyl)hydrazone, (E)-; CAS 343374-70-9; 343374-70-9; (E)-Chalcone (4-fluorophenyl)hydrazone derivative; Halogenated chalcone hydrazone.
EINECS	Contact for details

Quality Control

Our (E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Fluorophenyl)-2-Propen-1-One n-(4-Fluorophenyl)Hydrazone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and scale-up with custom purity grades and specifications tailored to your process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); for long-term storage, consider packaging under an inert gas such as nitrogen or argon in a sealed container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.