Description

(R)-(+)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide Solution is a high-purity, enantiomerically pure organozinc reagent, specifically the CAS NO 343338-26-1 compound, essential for advanced asymmetric synthesis. This compound is valued for its role as a chiral building block, enabling the stereoselective formation of carbon-carbon bonds in complex molecule construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value chiral intermediates.

Application

• Asymmetric Synthesis: Key reagent for enantioselective additions to carbonyl compounds and other electrophiles in pharmaceutical research.
• Chiral Intermediate Production: Used in the multi-step synthesis of complex, single-enantiomer molecules for drug candidates.
• Process Chemistry: Employed in the development and scale-up of efficient synthetic routes for API manufacturing.
• Methodology Development: Serves as a critical tool in academic and industrial labs for developing new catalytic and stoichiometric asymmetric transformations.
• Fine Chemical Synthesis: Building block for creating specialty chemicals, agrochemicals, and fragrances requiring specific stereochemistry.

Basic Information

Item	Details
Product Name	(R)-(+)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide Solution
CAS No.	343338-26-1
Molecular Formula	C7H13BrO2Zn
Molecular Weight	274.48 g/mol
Synonyms	(R)-3-Methoxy-2-methyl-3-oxopropylzinc bromide; (R)-(+)-Methyl 2-(bromozincio)propanoate; (R)-Methyl 2-(bromozincio)propionate; Zinc, bromo(1R)-1-methoxy-1-oxo-2-propanyl-; (R)-Methyl 2-(bromozincio)propanoate solution; Enantiopure organozinc reagent; Chiral zinc enolate equivalent
EINECS	Contact for details

Quality Control

Our (R)-(+)-3-Methoxy-2-Methyl-3-Oxopropylzinc Bromide Solution is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity, critical for reproducible asymmetric synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration, enantiomeric excess (ee), and solvent content. We adhere to cGMP standards where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; exposure to air, moisture, or light can degrade the reagent and reduce its efficacy. Handle and aliquot under inert conditions using standard Schlenk or glovebox techniques.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (Typical, other solvents available)
Assay (Titration)	≥ 95%
Enantiomeric Excess (ee)	≥ 99% (by Chiral HPLC or NMR)
Identification (IR / NMR)	Conforms to structure
Water Content (Karl Fischer)	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.