Description

Cyclopropane, (4-Chloro-1-Butynyl)- (9Ci) is a specialized organic building block featuring a cyclopropane ring fused with a chloro-substituted alkynyl chain. This unique molecular architecture makes it a valuable intermediate for advanced synthetic chemistry, particularly in the construction of complex, strained-ring systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those requiring strained carbocyclic frameworks.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclopropane moiety can enhance biological activity.
• Material Science Research: Acts as a precursor for advanced polymers or liquid crystals that incorporate rigid, three-membered ring structures.
• Cross-Coupling Reactions: The chloro and alkynyl functional groups make it a suitable substrate for Sonogashira, Suzuki, and other palladium-catalyzed coupling reactions.
• Academic & Industrial R&D: Employed in methodological studies and the synthesis of complex natural product analogs in university and corporate research laboratories.
• Ligand and Catalyst Development: Useful for constructing novel chiral or sterically hindered ligands for asymmetric catalysis.

Basic Information

Product Name	Cyclopropane, (4-Chloro-1-Butynyl)- (9Ci)
CAS No.	343268-23-5
Molecular Formula	C7H7Cl
Molecular Weight	126.58 g/mol
Synonyms	(4-Chloro-1-butynyl)cyclopropane; 1-Chloro-4-cyclopropylbut-3-yne; 4-Chloro-1-butynylcyclopropane; 3-Butyn-1-ol, 4-chloro-, 1-cyclopropyl derivative; Cyclopropane, (4-chloro-1-butyn-1-yl)-; (4-Chlorobut-1-yn-1-yl)cyclopropane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.