Description

6-Methoxy-5-Nitro-2-(Trifluoromethyl)Chromen-4-One is a specialized chromenone derivative, a high-value synthetic intermediate prized for its unique trifluoromethyl and nitro-substituted aromatic structure. This compound matters for its role in facilitating complex molecular synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a precursor for synthesizing advanced organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological development and novel heterocyclic chemistry research.
• Fluorine Chemistry: Acts as a valuable substrate for studying reactions involving fluorinated aromatic systems and for introducing fluorine-containing motifs into larger molecules.

Basic Information

Product Name	6-Methoxy-5-Nitro-2-(Trifluoromethyl)Chromen-4-One
CAS No.	342795-08-8
Molecular Formula	C₁₁H₆F₃NO₅
Molecular Weight	289.17 g/mol
Synonyms	6-Methoxy-5-nitro-2-(trifluoromethyl)-4H-chromen-4-one; 5-Nitro-6-methoxy-2-(trifluoromethyl)-4-chromone; 2-(Trifluoromethyl)-6-methoxy-5-nitro-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 6-methoxy-5-nitro-2-(trifluoromethyl)-; 6-Methoxy-5-nitro-2-trifluoromethylchromone; 342795-08-8; Chromen-4-one, 6-methoxy-5-nitro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-Nitro-2-(Trifluoromethyl)Chromen-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure consistency and traceability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.