Description

2-Amino-4-[4-(Difluoromethoxy)Phenyl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multi-functional chromene derivative with significant potential in advanced organic synthesis. This compound matters as a sophisticated chemical building block for pharmaceutical research and the development of novel agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and biological pathways.
• Material Science: Potential building block for advanced organic electronic materials and photoresists.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Library Synthesis: Valuable for creating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2-Amino-4-[4-(Difluoromethoxy)Phenyl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	342780-45-4
Molecular Formula	C19H18F2N2O3
Molecular Weight	360.36 g/mol
Synonyms	4H-Chromene-3-carbonitrile, 2-amino-4-[4-(difluoromethoxy)phenyl]-5,6,7,8-tetrahydro-7,7-dimethyl-5-oxo-; 2-Amino-4-(4-(difluoromethoxy)phenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 2-Amino-4-(4-difluoromethoxyphenyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile; Chromene derivative CAS 342780-45-4; DFMP-THC-CN
EINECS	Contact for details

Quality Control

Our 2-Amino-4-[4-(Difluoromethoxy)Phenyl]-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.