Description

2-Methanesulfonyl-6-Oxo-Hexahydro-Pyridazine-4-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and fine chemical industries for developing new drug candidates and scaling up production processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents.
• API Synthesis: Used in the multi-step synthesis of complex target molecules, particularly those containing fused pyridazine or hydropyridazine motifs.
• Process Chemistry: Employed in route scouting and optimization for scalable GMP manufacturing of drug substances.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Methanesulfonyl-6-Oxo-Hexahydro-Pyridazine-4-Carboxylic Acid Methyl Ester
CAS No.	339096-89-8
Molecular Formula	C8H12N2O6S
Molecular Weight	264.26 g/mol
Synonyms	Methyl 2-(methylsulfonyl)-6-oxohexahydropyridazine-4-carboxylate; 2-Methanesulfonyl-6-oxohexahydro-4-pyridazinecarboxylic Acid Methyl Ester; 6-Oxo-2-methanesulfonyl-hexahydro-pyridazine-4-carboxylic Acid Methyl Ester; Hexahydro-6-oxo-2-(methylsulfonyl)-4-pyridazinecarboxylic Acid Methyl Ester; CAS 339096-89-8
EINECS	Contact for details

Quality Control

Our 2-Methanesulfonyl-6-Oxo-Hexahydro-Pyridazine-4-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.